Is simvastatin still a good drug?

There was a report released recently about simvastatin being less effective than one of the more experienced statins at reducing certain measures of cardiovascular risk, despite its ability to lower the LDL cholesterol (the “bad” cholesterol) levels. 

My first word of caution regarding this: the study was performed in a very select group of individuals, people with a genetic disorder contributing to markedly elevated cholesterol levels that affects less than 1% of the population.  Right off the bat, you would be hard-pressed to apply the results of this study to the larger population (not sure why they even bothered).

It very well may not be as effective at reducing cardiac risk as we once thought, but until there is a more clear answer it shouldn’t be shunned quite yet.  As a generic drug, it is cheap and most often quite effective at lowering the LDL.  I expect there will be more detailed outcome studies comparing simvastatin with other statins. 

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: